Arlin
( Linezolid tablet & suspension )
Arlin® (Linezolid) is the first member of a new class of antibiotics known as oxazolidinones. Arlin (Linezolid) is a bacteriostatic agent indicated for the treatment of nosocomial infections involving Gram-positive organisms including methicillin-resistantStaph aureus (MRSA or ORSA), multi-resistant strains of Strep pneumoniae, and vancomycin-resistant Enterococcus faecium (VRE). Arlin (Linezolid) inhibits initiation of protein synthesis at the level of the ribosomes. It prevents the formation of the fmet- tRNA: mRNA: 30S subunit ternary complex. It also binds to the 50S ribosomal subunit in a region shared with chloramphenicol. However, unlike chloramphenicol, the oxazolidinones are not inhibitors of peptidyl transferase.
methicillin-susceptible and resistant strains
- Vancomycin resistant infections, including cases with concurrent bacteraemia.
- Nosocomial pneumonia & Community acquired pneumonia.
- Complicated skin and skin structure infections caused by Staphylococcus aureus
