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Prostate Health
Men, usually elderly, with diseases of prostate may suddenly be
unable to urinate at all. This condition is known as acute urinary
retention (AUR). So, relief should be prompt, so that the urine doesn't
continue to accumulate, stretch the bladder, and perhaps even back
up into the kidneys, causing them to fail. AUR is usually treated
by carefully inserting a tube, called a catheter, through the penis
or directly through the belly using a large needle. There it will
remain until the natural passage can be opened up, usually by surgery.
| What is the prostate gland and how does it function? |
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| The prostate is a gland about the size of a walnut that is situated
below the urinary bladder and in front of the rectum. The urethra
(a long tube that carries urine out of the body) passes through the
prostate.
The prostate gland produces a fluid that serves as the vehicle for
sperm. Although there will be implications if the prostate gland is
removed, it is not an essential organ and the body can function without
it.
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| Are all prostate tumors cancerous? |
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Several things never stop growing until they die --trees, reptiles,
the hair in ears and the prostate. Between the ages of 20 and 45,
the prostate gland doesn't grow much, but after that there's no stopping
it. Symptoms of this continuing growth don't usually show up before
age 60. At times, this tissue overgrowth is benign, meaning that the
cells do not contain cancer. This prostate condition is called benign
prostatic hypertrophy or BPH. Other times, abnormal cancerous cells
characterize the overgrowth of tissue and this is referred to as a
malignancy or cancer of the prostate.
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| How can a person know that he has benign prostatic hypertrophy
or BPH? |
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| The main symptom of BPH is a decrease in the flow of urine. Other
symptoms of BPH include:
- Hesitation in starting the urine flow
- Dribbling after emptying as much as a person can get out
- Feeling a great urgency to urinate (This is also a symptom
of a urine infection)
- Urinating many times during the night (The medical term for
this is- 'nocturia' and this can also be a symptom of heart failure)
- Feeling as if all the urine hasn't come out
Rarely the prostate will grow in such a way as to impinge upon the
rectum and cause constipation.
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| What are the traditional treatments of BPH? |
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Medical treatments
Proven medicinal treatments for BPH are alpha-adrenergic blockers
or alpha-blockers and finasteride.
Alpha-blockers relax the muscles that hold the urine in, while at
the same time strengthening the muscles that pump the urine out. They
can improve the urine flow, but they don't slow down the prostate's
growth.
Finasteride is a drug that interferes with the body's manufacturing
of male hormones. It has been shown to shrink the prostate by about
25% and to keep it shrunk for up to three years, if a person keeps
taking it. Longer studies are not yet available. These studies also
showed that finasteride reduced the need for prostate surgery by over
half. Two percent of men have sexual problems when taking finasteride.
Surgery
There are two surgical approaches for treating BPH - from the inside
(through the penis) and from the outside.
Transurethral resection of the prostate (TURP). The most common and
easiest route for prostate surgery for both the surgeon and the patient
is through the penis. Because the urine tube from the bladder to the
outside world is called a urethra, this procedure is known as a transurethral
resection of the prostate or TURP. TURP is simple and safe enough
that it can often be done in an outpatient setting. After numbing,
the urologist will insert a thin, rigid metal instrument called a
cystoscope into the penis. This instrument is both a telescope and
a cutting tool. Looking through it, the doctor can see the inside
of the urethra, the prostate and the bladder. He will look for tumors
and other abnormalities before beginning to cut away the prostate
from the inside, a process that can be likened to coring an apple.
After the procedure a catheter will remain in place until healing
is under way.
The main complication from a TURP is that many men during orgasm will
find their semen going back into the bladder instead of coming out
the way it used to. This is called retrograde ejaculation. A few men
have impotence or an inability to hold their urine (incontinence)
after prostate surgery.
Approaching the prostate from the outside is conventional surgery
through an incision somewhere in the skin. Only very large benign
prostates, cancerous ones and a few other special conditions require
this approach. There are several ways to get at it; but the surgeon's
choice which one he uses is much pretty. This requires hospitalization
and carries a higher risk of complications, including impotence and
incontinence.
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| Who is at risk for developing prostate cancer? |
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Researchers still do not know what causes prostate cancer. They have,
however, been able to identify risk factors that have consistently
been associated with prostate cancer. The role that some of the identified
risk factors play in the development of prostate cancer is less clear,
because research studies have provided conflicting results in some
areas.
Age: After age 50, the chance of developing prostate cancer
begins to increase. Over 80% of all prostate cancers occur in men
65 years and older.
Race: Prostate cancer is twice as prevalent among African-American
males as it is among their Caucasian-American counterparts.
Ethnicity: Prostate cancer is most common in North America
and northwestern Europe. It occurs less frequently in Asia, Africa,
Central America, and South America.
Diet: The results of most studies show that men who eat a high
fat diet have an increased chance of developing prostate cancer. Some
research has shown that men who eat higher fat diets tend to eat less
fruits and vegetables and more dairy products. These factors may also
play a part in the development of prostate cancer. Recent studies
have shown that a diet high in lycopenes (found in higher levels in
fruits and vegetables) and selenium, may lower the risk of developing
prostate cancer.
Exercise: Maintaining a healthy weight along with regular physical
activity may reduce the risk of prostate cancer.
Family history: Prostate cancer appears to have a genetic link.
Having a father or brother with the disease doubles a man's risk of
developing it. The risk gets even higher if several relatives have
been affected, especially if they were young at the time of diagnosis.
The recent discovery of the HPC1 gene will soon give more information
about the inherited risk of prostate cancer.
Vasectomy: Men who have undergone vasectomy (a surgical procedure
that renders them sterile) may have an increased risk of getting prostate
cancer, according to some studies. Findings in this area have been
inconsistent; while some studies have shown an increased risk after
vasectomy, others have not.
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| What is the best way to screen for prostate cancer? |
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Prostate cancer screening recommendations vary widely. Some organizations
believe that prostate cancer screening has not been proven to reduce
the number of overall deaths attributed to the disease. Other organizations,
like the American Cancer Society and the American Urological Association,
believe that the majority of evidence supports the view that prostate
cancer screening can save lives.
Digital rectal examination (DRE)
A digital rectal examination can be performed to screen for prostate
cancer as part of an annual physical examination in men age 50 or
above (and in younger men who are at increased risk). During this
test, a doctor inserts a gloved and lubricated finger into the rectum
to feel for any abnormally firm or irregularly shaped area of the
prostate that might be cancer. The prostate gland is located near
the rectum and many prostate tumors begin in an area that can be felt
on rectal examination. While the rectal examination may be a bit unpleasant,
it can be performed quickly.
Prostate specific antigen (PSA) test
The PSA test is a blood test, which measures a protein that is manufactured
by prostate cells. The American Cancer Society recommends that this
test be offered each year to men 50 and older with a life expectancy
of at least 10 years, and to younger men with higher prostate cancer
risk.
The PSA test results are reported as nanograms per milliliter or ng/ml.
Results under 4 ng/ml are usually considered normal. Results above
10 ng/ml are high and values between 4 and 10 are considered borderline.
The greater the PSA level, the greater the chance that prostate cancer
exists.
It is important to realize that the PSA is a screening tool and not
a diagnostic indicator for prostate cancer; PSA is used to estimate
the likelihood of prostate cancer. The level can be elevated in benign
conditions of the prostate and at times it may appear normal when
prostate cancer is present.
PSA levels are also useful in monitoring men who have had prostate
cancer. Often a rising PSA level can provide an early warning sign
that the prostate cancer is returning and early intervention can then
be instituted.
Transrectal ultrasound
Transrectal ultrasound (TRUS) may be suggested if the digital rectal
exam or PSA levels are abnormal. The test involves the insertion of
a probe into the rectum. Pictures are then recorded using sound waves
that create an image of the prostate gland.
During the TRUS, a biopsy may be obtained if a suspicious area of
the prostate is identified. The test is generally performed in a doctor's
office or outpatient setting. It usually takes less than 30 minutes
to perform.
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| How is the diagnosis of prostate cancer confirmed? |
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Since most early cases of prostate cancer produce no symptoms, it
may first be suspected after one of the screening tools is implemented.
Other signs may include difficulty in starting or maintaining a flow
of urine, increase in the urge to urinate, or blood in the urine.
Symptoms of advanced prostate cancer can include pain in the pelvis,
hips, spine or ribs, weight loss, weakness, and swelling of the lymph
nodes in the groin.
Once the suspicion of prostate cancer exists, a biopsy will be needed
to confirm the diagnosis and plan the best course of treatment. A
biopsy can be performed via the TRUS, whereby a selection of tissue
is removed from several areas of the prostate gland to get an adequate
sampling and determine how invasive the disease has become. The biopsy
can be performed in a doctor's office or outpatient setting.
After a biopsy is obtained, the tissue is sent to a laboratory and
examined by a pathologist. A report will be available in about 1 week.
If the biopsy is positive, meaning that cancer cells have been identified,
a grading system will be used to estimate the aggressiveness of the
tumor cells and the likelihood that the cancer will proliferate.
If the biopsy report indicates the presence of cancer, additional
testing will be needed to find out if the disease has spread beyond
the prostate gland to surrounding organs. This is referred to as staging.
The stage of cancer is the most important factor in determining treatment
options.
Tests that may be necessary to determine the stage of prostate cancer
include a computed tomography (CT) scan, magnetic resonance imaging
(MRI) scan, bone scan, and lymph node biopsy. |
How often a person will need to visit a doctor will depend on various
factors such as how close to normal the blood glucose levels are,
what symptoms a person may be experiencing, what other health conditions
are being treated for, and how comfortable the person is with current
treatment plan for managing diabetes.
The American Diabetes Association recommends that all patients with
type 2 diabetes should visit their doctor at least 2 to 4 times
per year. If the patient is newly diagnosed or experiencing symptoms
he/she may need to visit the doctor more often.
During each doctor visit the patient should be prepared to discuss
about blood glucose readings. The doctor will record the weight
and blood pressure at each visit. As part of routine physical examination
the doctor will also check the eyes and feet to screen for diabetic
complications. An annual examination by an eye doctor is also recommended.
Several blood tests to check cholesterol, lipids, and glycosylated
hemoglobin (a blood test that gives information about how well controlled
the blood sugars have been during the last 2 to 3 months) may also
be done. A urine test should also be performed to check for protein.
During each office visit, the patient should have an opportunity
to review treatment plan and set goals together with physician.
It should be remembered that diabetes management is a joint effort
that will only produce good results when both the patient and doctor
work together cooperatively. |
The commonest manifestation is an itchy rash that develops over a few days, after skin contact with a substance. The affected area first becomes itchy, then red and swollen with vesicles (water bubbles).
Although usually confined to the area of contact, sometimes strikingly so the rash can spread to other parts of the body.
occasionally the rash is more chronic, manifesting as an itchy patch that does not heal for weeks or even months. This usually occurs when there is frequent contact with the substance e.g. a watch strap. The rash resulting from contact allergy is called allergic contact dermatitis. |
A substance that can cause contact allergy is called a contact allergen. Common contact allergens are:
- metals e.g. nickel in watch straps, chrome in cement
- skin care products e.g. fragrances, lanolin
- medication e.g. flavine, neomycin.
A skin test called a patch test is used to confirm contact allergy. The upper back is used as a test site. A small amount of the suspected contact allergen (diluted to a non-irritant concentration) is applied onto the skin in an aluminium chamber and sealed with hypoallergenic tape. Usually, several suspected allergens are tested simultaneously. They are left on the skin for 48 hours and read at 48 and 96 hours. A positive reaction indicates that he patient is allergic to the test substance. This is a very safe procedure. |
Very often it is. An example of the need for a patch test is when a skin rash has persisted for a long time. Many skin care products and medication would have been tried. It is necessary to identify the cause of contact allergy. A patch test will help to ascertain the cause.
Another situation whereby a patch test is important is when a dermatitis is suspected to be due to work. There are many substances in the workplace that may cause contact allergy. |
In many cases, removing the cause i.e. the allergen from skin contact will result in a cure. Usually, once allergy to a substance has developed, it remains for life. That is to say, future contact with the substance will result in an allergic contact dermatitis again. This is exactly like a drug allergy. It is advisable for patients to carry a card to remind themselves and their doctors of their contact allergy. |
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