Amdopril
( Amlodipine and Benazepril Capsule )
The combination of Amlodipine and Benazepril is used to treat high blood pressure. Benazepril has an antihypertensive effect even in patients with low-renin hypertension. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. The antihypertensive effect of a single dose persisted for 24 hours. Once-daily doses of Benazepril/Amlodipine using Benazepril doses of 10-20 mg and Amlodipine doses of 2.5-10 mg decreased seated pressure (systolic/diastolic) 24 hours after dosing by about 10-25/6-13 mmHg.
- For your patients who need more than an ACE inhibitor
- Offers first line therapy in hypertension with diabetes
- Ensures aggressive management of BP in hypertension with diabetes
- Once daily fixed dose combination ensures patients Compliance
