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What is NapaDol®?
NapaDol® is a combination of two Paracetamol 325 mg and Tramadol 37.5 mg tablet. Tramadol Hydrochloride is an opioid analgesic that acts on the central nervous system. Tramadol is pure non selective agonists of the m, d, and k opioid receptors with a higher affinity for the m receptors. Unlike morphine, Tramadol Hydrochloride has no respiratory depressant effect. Paracetamol (acetaminophen) is a pain reliever and a fever reducer which is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. Combination of Paracetamol and Tramadol exerts a synergistic effect and subsides mutual side effects.
When to take NapaDol®?
NapaDol® is indicated for the symptomatic treatment of moderate to severe pain.
How to take NapaDol®?
For the management of pain, the recommended dose is 1 or 2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day. The dosing interval should not be less than six hours.
Who should not take NapaDol®?
NapaDol® is not recommended in patients under 18 years of age. NapaDol® should not be used in patients who have hypersensitivity to Tramadol Hydrochloride, Paracetamol or to any of the excipients of the medicinal product. It is contraindicated in case of acute intoxication with alcohol, hypnotic drugs, centrally‐acting analgesics, opioids or psychotropic drugs. It should not be administered to patients who are receiving monoamine oxidase inhibitors or within two weeks of their withdrawal, who have severe hepatic impairment and epilepsy not controlled by treatment.
How NapaDol® works?
Tramadol in NapaDol® works by changing the way the body senses pain, meaning that Tramadol modifies the way in which the body reacts to pain. The precise mechanism of the analgesic properties of Paracetamol, the other component of NapaDol® is unknown and may involve central and peripheral effects.
How supplied?
Box containing 30 tablets in 3x10’s blister strips. Each film coated tablet contains Paracetamol BP 325 mg & Tramadol Hydrochloride BP 37.5 mg.
Prescribing Information
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